Article
p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck.
British journal of cancer - 1 Apr 1995
Nylander K, Nilsson P, Mehle C, Roos G
Abstract excerpt
Thirty-three patients with squamous cell carcinoma of the head and neck region were studied concerning p53 protein expression and mutations in exons 4-9 of the p53 gene using immunohistochemistry, polymerase chain reaction (PCR)-single strand conformation polymorphism analysis and DNA sequencing....
Topics
- Base Sequence
- Carcinoma, Squamous Cell
- Cell Division
- DNA Mutational Analysis
- DNA Primers
- DNA, Neoplasm
- Exons
- Gene Expression
- Genes, p53
- Genetic Variation
- Head and Neck Neoplasms
- Humans
- Immunohistochemistry
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Proliferating Cell Nuclear Antigen
- Sequence Deletion