Role of cytoplasmic tail phosphorylation sites of platelet-activating factor receptor in agonist-induced desensitization.

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Article

Role of cytoplasmic tail phosphorylation sites of platelet-activating factor receptor in agonist-induced desensitization.

The Journal of biological chemistry - 2 Sept 1994

Takano T, Honda Z, Sakanaka C, Izumi T, Kameyama K, Haga K, Haga T, Kurokawa K, Shimizu T

Abstract excerpt

The platelet-activating factor (PAF) receptor couples with multiple signaling pathways such as activation of phospholipase C, phospholipase A2, and mitogen-activated protein kinase and the inhibition of adenylate cyclase. The PAF-induced signals are attenuated by repetitive or long standing appli...

Topics

Amino Acid Sequence
Animals
Base Sequence
CHO Cells
Calcium
Cricetinae
Cricetulus
Cyclic AMP-Dependent Protein Kinases
Cytoplasm
Guinea Pigs
Humans
Inositol 1,4,5-Trisphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kinetics

Molecular Sequence Data

Mutation

Oligodeoxyribonucleotides

Phosphorylation

Platelet Activating Factor

Source

Open in PubMed

Identifiers

PMID: 8071375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8071375-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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