Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice.

doi:10.1016/s0163-7827(99)00016-8

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Article

Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice.

Progress in lipid research - 1 Jan 2000

Ishii S, Shimizu T

Abstract excerpt

Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. Although PAF was initially recognized for its potential to induce platelet aggregation and secretion, intense investigations have elucidated potent biological actions of PAF in a broad range of cell types and tissues, many of which also produce the molecule. PAF acts by binding to a...

Topics

Amino Acid Sequence
Animals
Guinea Pigs
Humans
Inflammation
Mice
Mice, Knockout
Mice, Transgenic
Molecular Sequence Data
Phenotype
Platelet Activating Factor
Platelet Membrane Glycoproteins
Protein Binding
Rats
Receptors, Cell Surface
Receptors, G-Protein-Coupled
Sequence Alignment
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 10729607
DOI: 10.1016/s0163-7827(99)00016-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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