Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Platelet-activating factor receptor.

Prostaglandins & other lipid mediators - 1 Aug 2002

Ishii Satoshi, Nagase Takahide, Shimizu Takao

Abstract excerpt

Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. Although PAF was named for its potential to induce platelet aggregation, intense investigations have elucidated potent biological actions of PAF in a broad range of cell types and tissues. PAF acts by binding to a unique G-protein-coupled seven transmembrane receptor, and activates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Platelet Membrane Glycoproteins
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Receptors, Cell Surface

Share to Receptors, G-Protein-Coupled

Share to Shock, Septic

Share to Signal Transduction

Source

Identifiers

PMID: 12432946
DOI: 10.1016/s0090-6980(02)00058-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Platelet-activating factor receptor.PMID 12432946Read ↗

Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice.Semantic proximity Read ↗

Single nucleotide polymorphism of human platelet-activating factor receptor impairs G-protein activation.Semantic proximity Read ↗

In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice.Semantic proximity Read ↗

Cell surface receptors in lysophospholipid signaling.Semantic proximity Read ↗

Lysophospholipid G protein-coupled receptors.Semantic proximity Read ↗

PAFR in adipose tissue macrophages is associated with anti-inflammatory phenotype and metabolic homoeostasis.Semantic proximity Read ↗

Mutation of a putative amphipathic alpha-helix in the third intracellular domain of the platelet-activating factor receptor disrupts receptor/G protein coupling and signaling.Semantic proximity Read ↗

Signalling or binding: the role of the platelet-activating factor receptor in invasive pneumococcal disease.Semantic proximity Read ↗

Functional characterization of lysophosphatidic acid receptor 1 mutants identified in rat cancer tissues.Semantic proximity Read ↗

Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).Semantic proximity Read ↗

Molecular cloning and expression of platelet-activating factor receptor from human leukocytes.Semantic proximity Read ↗

Lysophosphatidic acid receptors in cancer pathobiology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.