Article
Molecular basis of the motheaten phenotype.
Immunological reviews - 1 Apr 1994
Tsui F W, Tsui H W
Abstract excerpt
Mice homozygous for the autosomal recessive motheaten (me) or the allelic viable motheaten (mev) mutations manifest a unique immunological disease associated with severe immunodeficiency and autoimmunity. Over the past few years, our group has used the motheaten mouse as a model system for elucid...
Topics
- Amino Acid Sequence
- Animals
- Autoimmune Diseases
- Base Sequence
- Bone Marrow
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Phenotype
- Point Mutation
- Protein Tyrosine Phosphatases
- Severe Combined Immunodeficiency