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Article

Analysis of coreceptor versus accessory molecule function of CD8 as a correlate of exogenous peptide concentration.

Molecular immunology - 1 Aug 1994

Knall C, Ingold A, Potter T A

Abstract excerpt

Substitution in the alpha 3 domain of class I molecules can ablate the recognition of target cells by CD8 dependent cytotoxic T lymphocytes. This effect has been attributed to a destruction of the CD8 alpha binding site on the class I molecule, a hypothesis which is consistent with results obtained in conjugate binding assays. To assess the relative contribution to CTL activation of CD8 functioning as either a...

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PMID: 8065371
DOI: 10.1016/0161-5890(94)90007-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Analysis of coreceptor versus accessory molecule function of CD8 as a correlate of exogenous peptide concentration.PMID 8065371Read ↗

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