Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunoglobulin kappa light chain gene alleles are not associated with primary Sjögren's syndrome.

Genes and immunity - 1 Oct 2002

Downie-Doyle S, Lester S, Bardy P, Gordon T, Rischmueller M, Pile K

Abstract excerpt

The immunoglobulin kappa (Km) light chain gene is polymorphic and is believed to play a role in the pathology of infectious and autoimmune diseases. Polymorphisms within the constant region of the Km gene encode three alleles designated Km1, Km1,2 and Km3. Previous studies using serological detection of Km allotypes reported associations between specific Km allotypes, systemic lupus erythematosus and the presence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin kappa-Chains

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Sjogren's Syndrome

Source

Identifiers

PMID: 12215905
DOI: 10.1038/sj.gene.6363853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunoglobulin kappa light chain gene alleles are not associated with primary Sjögren's syndrome.PMID 12215905Read ↗

Immunoglobulin KM and GM gene polymorphisms modify the clinical presentation of primary Sjögren's syndrome.Semantic proximity Read ↗

Systemic lupus erythematosus is not associated with allotypic markers of immunoglobulin kappa in Caucasians.Semantic proximity Read ↗

Km typing with PCR: application to population screening.Semantic proximity Read ↗

Mannose-binding lectin-low genotypes are associated with milder systemic and immunological disease expression in primary Sjögren's syndrome.Semantic proximity Read ↗

Polymerase chain reaction-based genotyping for allotypic markers of immunoglobulin kappa shows allelic association of Km with kappa variable segment.Semantic proximity Read ↗

Pemphigus is not associated with allotypic markers of immunoglobulin kappa.Semantic proximity Read ↗

Km genotyping by polymerase chain reaction (PCR) using allele-specific amplification primers.Semantic proximity Read ↗

Absence of somatic MYD88 L265P mutations in patients with primary Sjogren's syndrome.Semantic proximity Read ↗

Immunoglobulin allotypes are not associated with HLA-antigens, autoantibodies and clinical symptoms in systemic lupus erythematosus. Members of the SLE Study Group.Semantic proximity Read ↗

Association of KM genotype with bullous pemphigoid.Semantic proximity Read ↗

T-cell receptor alpha, beta, gamma, and delta chain gene microsatellites show no association with multiple sclerosis.Semantic proximity Read ↗

Distribution of MHC class II alleles in primary systemic vasculitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.