Article
Immunoglobulin allotypes are not associated with HLA-antigens, autoantibodies and clinical symptoms in systemic lupus erythematosus. Members of the SLE Study Group.
Rheumatology international - 1 Jan 1991
Hartung K, Coldewey R, Röther E, Pirner K, Specker C, Schendel D, Stangel W, Stannat-Kiessling S, de Lange G G
Abstract excerpt
Immunoglobulin heavy chain (G1m, G2m, G3m, A2m) and kappa light chain (Km) allotype and phenotype frequencies of 323 central European Caucasian patients with systemic lupus erythematosus (SLE) were examined and correlated with various genetic, serologic and clinical markers of SLE. No significant associations were found between immunoglobulin allotypes or phenotypes and all 20 parameters tested (nephritis,...
Topics
- Autoantibodies
- Europe
- Genetic Markers
- HLA Antigens
- Humans
- Immunoglobulin Allotypes
- Immunoglobulin Heavy Chains
- Immunoglobulin kappa-Chains
- Lupus Erythematosus, Systemic
- Phenotype