A mutation in the Ter gene causing increased susceptibility to testicular teratomas maps to mouse chromosome 18.

doi:10.1038/ng0494-363

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Article

A mutation in the Ter gene causing increased susceptibility to testicular teratomas maps to mouse chromosome 18.

Nature genetics - 1 Apr 1994

Asada Y, Varnum D S, Frankel W N, Nadeau J H

Abstract excerpt

Little is known about inherited susceptibility to spontaneous germ cells tumours in humans or other species. The Ter mutation in laboratory mice is novel in that it acts codominantly to reduce germ cell numbers on many inbred strain backgrounds and to enhance dramatically inherited predisposition...

Topics

Animals
Base Sequence
Chromosome Mapping
Crosses, Genetic
DNA
Genetic Linkage
Genetic Predisposition to Disease
Male
Mice
Mice, Inbred Strains
Molecular Sequence Data
Muridae
Mutation
Polymerase Chain Reaction
Teratocarcinoma
Teratoma
Testicular Neoplasms
Testis

Source

Open in PubMed

Identifiers

PMID: 8054975
DOI: 10.1038/ng0494-363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8054975-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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