Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosome X modulates incidence of testicular germ cell tumors in Ter mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2007

Hammond Shirley, Zhu Rui, Youngren Kirsten K, Lam Josephine, Anderson Philip, Matin Angabin

Abstract excerpt

Germ cell tumor development in humans has been proposed to be part of testicular dysgenesis syndrome (TDS), which manifests as undescended testes, sterility, hypospadias, and, in extreme cases, as germ cell tumors. Males of the Ter mouse strain show interesting parallels to TDS because they either lack germ cells and are sterile or develop testicular germ cell tumors. We found that these defects in Ter mice are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crosses, Genetic
Share to Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Neoplasms, Germ Cell and Embryonal

Share to Testicular Neoplasms

Share to Testis

Share to X Chromosome

Share to Y Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 18049836
DOI: 10.1007/s00335-007-9075-8
PMCID: PMC2647741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosome X modulates incidence of testicular germ cell tumors in Ter mice.PMID 18049836Read ↗

The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.Semantic proximity Read ↗

Search for testicular cancer gene hits dead-end.Semantic proximity Read ↗

The ter mutation in the rat Dnd1 gene initiates gonadal teratomas and infertility in both genders.Semantic proximity Read ↗

Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic backgroundSemantic proximity Read ↗

Genetic control of susceptibility to spontaneous testicular germ cell tumors in mice.Semantic proximity Read ↗

Trans-generational epistasis between Dnd1Ter and other modifier genes controls susceptibility to testicular germ cell tumors.Semantic proximity Read ↗

Identification of genomic locus responsible for experimentally induced testicular teratoma 1 (ett1) on mouse Chr 18.Semantic proximity Read ↗

Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis.Semantic proximity Read ↗

A mutation in the Ter gene causing increased susceptibility to testicular teratomas maps to mouse chromosome 18.Semantic proximity Read ↗

Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells.Semantic proximity Read ↗

Susceptibility to testicular germ-cell tumours in a 129.MOLF-Chr 19 chromosome substitution strain.Semantic proximity Read ↗

MC4R mutant mice develop ovarian teratomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.