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Article

Allele- and haploid-specific product generated by alternative splicing from a mouse t complex responder locus candidate.

Nature - 17 Jan 1991

Cebra-Thomas J A, Decker C L, Snyder L C, Pilder S H, Silver L M

Abstract excerpt

Mouse t haplotypes represent a variant form of chromosome 17 that has evolved the ability to propagate through natural populations by the phenomenon of 'transmission ratio distortion' (TRD), in which heterozygous +/t males transmit their t-carrying chromosome to 95% or more of their offspring. Although multiple t-associated loci have a role in expression of this phenotype, only one--the t complex responder (Tcr)...

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Identifiers

PMID: 1987476
DOI: 10.1038/349239a0

Genes

TRD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Allele- and haploid-specific product generated by alternative splicing from a mouse t complex responder locus candidate.PMID 1987476Read ↗

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Functional analysis of a t complex responder locus transgene in mice.Semantic proximity Read ↗

ORFless, intronless, and mutant transcription units in the mouse t complex responder (Tcr) locus.Semantic proximity Read ↗

Segregation distortion of mouse t haplotypes the molecular basis emerges.Semantic proximity Read ↗

Transmission Ratio Distortion in MiceSemantic proximity Read ↗

Retention of gene products in syncytial spermatids promotes non-Mendelian inheritance as revealed by the t complex responder.Semantic proximity Read ↗

Sequence of the t complex Tcp-10at gene and examination of the Tcp-10t gene family.Semantic proximity Read ↗

Identification of a germ-cell-specific transcriptional repressor in the promoter of Tctex-1.Semantic proximity Read ↗

The mouse t complex distorter-3 (Tcd-3) locus and transmission ratio distortion.Semantic proximity Read ↗

Novel patterns of expression and recruitment of new genes on the t-haplotype, a mouse selfish chromosome.Semantic proximity Read ↗

Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotypeSemantic proximity Read ↗

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