Article
Concerted evolution of the mouse Tcp-10 gene family: implications for the functional basis of t haplotype transmission ratio distortion.
Genomics - 1 Jan 1992
Pilder S H, Decker C L, Islam S, Buck C, Cebra-Thomas J A, Silver L M
Abstract excerpt
The mouse Tcr locus is defined by its central role in the transmission ratio distortion phenotype characteristic of t haplotypes. A molecular candidate for Tcr has been identified in the form of a gene--Tcp-10b--expressed during spermatogenesis. Tcp-10b is one member of a multigene family present in two to four copies on different homologs of chromosome 17. The coding regions of the Tcp-10 genes present within...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Biological Evolution
- Chromosome Deletion
- Chromosome Mapping
- Haplotypes
- Intracellular Signaling Peptides and Proteins
- Male
- Mice
- Microtubule-Associated Proteins
