Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetic analysis of flow-sorted ovarian tumour cells: improved detection of loss of heterozygosity.

British journal of cancer - 1 Aug 1994

Abeln E C, Corver W E, Kuipers-Dijkshoorn N J, Fleuren G J, Cornelisse C J

Abstract excerpt

Detection of loss of heterozygosity (LOH) is usually performed on homogenised tumour specimens. In this type of analysis samples with a low percentage of tumour cells have to be excluded and possible intra-tumour heterogeneity is obscured. In this study we report the application of polymerase chain reaction (PCR)-driven LOH detection with in total 22 microsatellite markers for chromosome 1q, 3p, 3q, 4p, 6p, 6q,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Flow Cytometry

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 8054273
DOI: 10.1038/bjc.1994.289
PMCID: PMC2033519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetic analysis of flow-sorted ovarian tumour cells: improved detection of loss of heterozygosity.PMID 8054273Read ↗

PCR-based microsatellite polymorphisms in the detection of loss of heterozygosity in fresh and archival tumour tissue.Semantic proximity Read ↗

Microdissection as a means to verify allelic imbalance in tumour biology samples.Semantic proximity Read ↗

Microdissection-based mutational genotyping of serous borderline tumors of the ovary.Semantic proximity Read ↗

Molecular genetic changes in human epithelial ovarian malignancies.Semantic proximity Read ↗

Genetic analysis of benign ovarian tumors.Semantic proximity Read ↗

Allelotyping defines minimal imbalance at chromosomal region 17q25 in non-serous epithelial ovarian cancers.Semantic proximity Read ↗

Comparison of genetic changes in frozen biopsies and microdissected archival material from the same colorectal liver metastases.Semantic proximity Read ↗

Mapping of chromosome 3p deletions in human epithelial ovarian tumors.Semantic proximity Read ↗

Quantitation of the allelic imbalance provides evidence on tumour heterogeneity: a hypothesis.Semantic proximity Read ↗

Molecular genetic changes associated with ovarian cancer.Semantic proximity Read ↗

Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci.Semantic proximity Read ↗

Polymerase chain reaction allelotyping of human ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.