Molecular genetic changes associated with ovarian cancer.

doi:10.1006/gyno.1994.1285

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Article

Molecular genetic changes associated with ovarian cancer.

Gynecologic oncology - 1 Nov 1994

Weitzel J N, Patel J, Smith D M, Goodman A, Safaii H, Ball H G

Abstract excerpt

Multiple specific chromosomal deletions can be found in human epithelial ovarian cancer by cytogenetic analysis or molecular techniques. Somatic allelic deletion or loss of heterozygosity (LOH) in a tumor is considered circumstantial evidence for the location of tumor suppressor genes. We have ex...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Biomarkers, Tumor
Chromosome Deletion
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 9
DNA, Neoplasm
Female
Genes, APC
Heterozygote
Humans
Middle Aged

Source

Open in PubMed

Identifiers

PMID: 7959292
DOI: 10.1006/gyno.1994.1285

Genes

APC
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7959292-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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