Article
Variation in expression of porcine xenogeneic antigens.
Transplantation - 15 Aug 1994
Geller R L, Rubinstein P, Platt J L
Abstract excerpt
The rejection of organs transplanted between phylogenetically disparate animals such as pigs and primates is thought to be initiated by binding of naturally occurring antibodies of the recipient to blood vessels in the donor organ. The major porcine target antigens are a triad of glycoproteins, gp115/135, which are expressed on endothelial cells and platelets of all animals tested to date. Whether expression of...
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