Article
Lack of variation in alphaGal expression on lymphocytes in miniature swine of different genotypes.
Xenotransplantation - 1 Feb 1999
Chae S J, Kramer A D, Zhao Y, Arn S, Cooper D K, Sachs D H
Abstract excerpt
BACKGROUND: Gal(alpha)1-3Gal epitopes (alphaGal) have been demonstrated to be present on tissues of all pig breeds tested to-date and are the major target for human anti-(alpha)galactosyl (alphaGal) antibodies. We investigated members of an MHC-inbred miniature swine herd to assess whether there was an association between genotype and expression of alphaGal. Identification of a low expressor genotype would...
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