Article
Molecular determinants of bioactivity of the Saccharomyces cerevisiae lipopeptide mating pheromone.
The Journal of biological chemistry - 5 Aug 1994
Caldwell G A, Wang S H, Xue C B, Jiang Y, Lu H F, Naider F, Becker J M
Abstract excerpt
The a-factor of Saccharomyces cerevisiae (YIIKGVF-WDPAC(Farnesyl)-OCH3) is a peptide pheromone in which post-translational modification with a farnesyl isoprenoid and carboxyl methyl group is required for export and bioactivity. Truncated and carboxyl-terminal modified analogs of the a-factor wer...
Topics
- Amino Acid Sequence
- Chromatography, High Pressure Liquid
- Chromatography, Thin Layer
- Mating Factor
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Peptide Fragments
- Peptides
- Phenotype
- Protein Conformation
- Saccharomyces cerevisiae