Article
Total in vitro maturation of the Saccharomyces cerevisiae a-factor lipopeptide mating pheromone.
Biochemical and biophysical research communications - 15 Nov 1990
Marcus S, Caldwell G A, Xue C B, Naider F, Becker J M
Abstract excerpt
The a-factor mating pheromone, produced by Saccharomyces cerevisiae a haploid cells, is post-translationally modified in a manner analogous to that of the ras proto-oncogene product. A consensus C-terminal amino acid sequence, -CAAX (C is cysteine, A is aliphatic amino acid, and X is any amino acid), is the target of these modifications, which include isoprenylation (essential for Ras function), proteolysis of...
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