Context-dependent activation and evolutionary buffering of a mating pheromone in fission yeast.

Abstract excerpt

The evolution of mating signals drives reproductive isolation and speciation across diverse lineages. However, how short peptide pheromones, typically subject to strong structural constraints, achieve functional diversification remain unclear. In the fission yeast Schizosaccharomyces pombe, a previously established library of 153 single-amino acid variants of the mating pheromone M-factor was applied to...

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• Biological Evolution
• Evolution, Molecular
• Mutation
• Pheromones
• Reproduction