Article
Substrate specificity determinants in the farnesyltransferase beta-subunit.
Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 1997
Trueblood C E, Boyartchuk V L, Rine J
Abstract excerpt
Protein prenyltransferases catalyze the covalent attachment of isoprenoid lipids (farnesyl or geranylgeranyl) to a cysteine near the C terminus of their substrates. This study explored the specificity determinants for interactions between the farnesyltransferase of Saccharomyces cerevisiae and it...
Topics
- Alkyl and Aryl Transferases
- Alleles
- Amino Acid Sequence
- Base Sequence
- Farnesyltranstransferase
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Protein Prenylation
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid
- Substrate Specificity