Article
Tumor suppressor genes encoding proteins required for cell interactions and signal transduction in Drosophila.
Development (Cambridge, England). Supplement - 1 Jan 1993
Bryant P J, Watson K L, Justice R W, Woods D F
Abstract excerpt
Tumor suppressor genes, whose products are required for the control of cell proliferation, have been identified by their mutant phenotype of tissue overgrowth. Here we describe recent work on the molecular identification of tumor suppressor genes that function in two different cell types of the Drosophila larva: the blood cells, and the undifferentiated epithelial cells of developing imaginal discs. Mutations in...
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