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Article

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia.

The Journal of cell biology - 1 Sept 1996

Woods D F, Hough C, Peel D, Callaini G, Bryant P J

Abstract excerpt

The Discs large (Dlg) protein of Drosophila is the prototypic member of a growing family of proteins termed membrane-associated guanylate kinase homologs (MAGUKs). The MAGUKs are composed of a series of peptide domains that include one or three DHR/PDZs, an SH3, and a region homologous to guanyla...

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Identifiers

PMID: 8830775
DOI: 10.1083/jcb.134.6.1469
PMCID: PMC2120992

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8830775-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia.PMID 8830775Read ↗

Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large.Semantic proximity Read ↗

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Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene.Semantic proximity Read ↗

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.Semantic proximity Read ↗

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Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble.Semantic proximity Read ↗

Discs large 5, an Essential Gene in Drosophila, Regulates Egg Chamber Organization.Semantic proximity Read ↗

On the role of the MAGUK proteins encoded by Drosophila varicose during embryonic and postembryonic development.Semantic proximity Read ↗

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