Article
Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Apr 1994
Szabo E, Preis L H, Birrer M J
Abstract excerpt
Previous studies have shown that phorbol ester induced macrophage differentiation in the leukemic cell line U-937 is tightly linked to the expression of the c-jun protooncogene and the generation of AP-1 transcriptional activity. We expressed the c-jun protooncogene in U-937 cells to examine the role of c-jun in the differentiation of these cells. AP-1 DNA binding activity and the expression of AP-1 controlled...
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