Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Apr 1994

Szabo E, Preis L H, Birrer M J

Abstract excerpt

Previous studies have shown that phorbol ester induced macrophage differentiation in the leukemic cell line U-937 is tightly linked to the expression of the c-jun protooncogene and the generation of AP-1 transcriptional activity. We expressed the c-jun protooncogene in U-937 cells to examine the...

Topics

Animals
Cell Differentiation
Cell Division
Cell Line
Cloning, Molecular
Gene Expression
Genes, jun
Humans
Macrophages
Mice
Phenotype
Proto-Oncogene Proteins c-jun

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transfection

Source

Identifiers

PMID: 8043518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8043518-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.PMID 8043518Read ↗

Constitutively active MAP kinase kinase (MEK1) stimulates SAP kinase and c-Jun transcriptional activity in U937 human leukemic cells.Semantic proximity Read ↗

Proto-Oncogenes of the <i><i>fos/jun</i></i> Family of Transcription Factors are Positive Regulators of Myeloid DifferentiationSemantic proximity Read ↗

The mitogen-activated protein kinase pathway inhibits ceramide-induced terminal differentiation of a human monoblastic leukemia cell line, U937.Semantic proximity Read ↗

Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.Semantic proximity Read ↗

MafB is an inducer of monocytic differentiation.Semantic proximity Read ↗

Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.Semantic proximity Read ↗

Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta.Semantic proximity Read ↗

Activation of the human NPY gene during neuroblastoma cell differentiation: induced transcriptional activities of AP-1 and AP-2.Semantic proximity Read ↗

JC Virus Multiplication in Human Hematopoietic Progenitor Cells Requires the NF-1 Class D Transcription FactorSemantic proximity Read ↗

Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation.Semantic proximity Read ↗

Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription.Semantic proximity Read ↗

Gene regulation and genetic susceptibility to neoplastic transformation: AP-1 and p80 expression in JB6 cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.