Article
Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jul 1994
Schambye H T, Hjorth S A, Bergsma D J, Sathe G, Schwartz T W
Abstract excerpt
To characterize binding sites for nonpeptide angiotensin antagonists on the human angiotensin II receptor type 1 (AT1 receptor) we have systematically exchanged segments of the human receptor with corresponding segments from a homologous Xenopus laevis receptor, which does not bind the nonpeptide...
Topics
- Amino Acid Sequence
- Angiotensin II
- Angiotensin Receptor Antagonists
- Animals
- Binding Sites
- Humans
- Molecular Sequence Data
- Molecular Structure
- Mutation
- Peptides
- Receptors, Angiotensin
- Xenopus laevis