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Article

Analysis of the MHC class II encoded components of the HLA class I antigen processing pathway in ankylosing spondylitis.

Annals of the rheumatic diseases - 1 Jan 1994

Burney R O, Pile K D, Gibson K, Calin A, Kennedy L G, Sinnott P J, Powis S H, Wordsworth B P

Abstract excerpt

OBJECTIVES: The evaluation of the role of polymorphism within the class II encoded antigen processing genes, LMP2 and TAP, in susceptibility to ankylosing spondylitis (AS). METHODS: Eighty five patients with ankylosing spondylitis, 35 B27 positive healthy controls, and 55 unrelated healthy controls were studied. TAP1 and TAP2 alleles were assigned by ARMS PCR, and LMP2 alleles were assigned by restriction enzyme...

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Source

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Identifiers

PMID: 8311558
DOI: 10.1136/ard.53.1.58
PMCID: PMC1005245

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Analysis of the MHC class II encoded components of the HLA class I antigen processing pathway in ankylosing spondylitis.PMID 8311558Read ↗

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TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis.Semantic proximity Read ↗

Polymorphism in the LMP2 gene influences susceptibility to extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis.Semantic proximity Read ↗

Analysis of MHC encoded antigen-processing genes TAP1 and TAP2 polymorphisms in sarcoidosis.Semantic proximity Read ↗

TAP1 and TAP2 polymorphisms associated with ankylosing spondylitis in genetically homogenous Chinese Han population.Semantic proximity Read ↗

LMP2 polymorphism is associated with extraspinal disease in HLA-B27 negative Caucasian and Mexican Mestizo patients with ankylosing spondylitis.Semantic proximity Read ↗

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TAP1 and TAP2 polymorphism in HLA-B27-positive subpopulations: no allelic differences in ankylosing spondylitis and reactive arthritis.Semantic proximity Read ↗

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