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Article

[Allelic polymorphism of genes encoding catalytic immunoproteasome subunits and its functional meaning].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) - 1 Jan 2005

Dosenko V Ie, Mykhal'chuk D V, Zahoriĭ V Iu, Khaĭtovych M V, Moĭbenko O O

Abstract excerpt

Proteasomal activity in isolated monocytes from subjects with different variants of large multifunctional proteases genes -LMP2 (Arg60-->His allelic polymorphism) and LMP7 (Lys145-->Gln allelic polymorphism) was determined. Trypsin-like activity of proteasome was 1.6-times (P = 0.19) higher at Arg/Arg genotype comparing to His/His genotype, and 2-fold lower than at Arg/His genotype. The highest chymotrypsin-like...

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PMID: 16485847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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