Polymorphisms, but lack of mutations or instability, in the promotor region of the mitochondrial genome in human colonic tumors.

Article

Polymorphisms, but lack of mutations or instability, in the promotor region of the mitochondrial genome in human colonic tumors.

Cancer research - 15 Jul 1994

Heerdt B G, Chen J, Stewart L R, Augenlicht L H

Abstract excerpt

The region of the human mitochondrial D-loop has been sequenced from DNA of colonic tumors and paired normal colonic tissue to determine if mutations in the promotors for the heavy or light strands are responsible for the decrease in mitochondrial gene expression present in colonic tumors. No mut...

Topics

Base Sequence
Colonic Neoplasms
DNA, Mitochondrial
Humans
Molecular Sequence Data
Mutation
Polymorphism, Genetic
Promoter Regions, Genetic

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