Acetylation phenotype and cutaneous hypersensitivity to trimethoprim-sulphamethoxazole in HIV-infected patients.

doi:10.1097/00002030-199403000-00006

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Article

Acetylation phenotype and cutaneous hypersensitivity to trimethoprim-sulphamethoxazole in HIV-infected patients.

AIDS (London, England) - 1 Mar 1994

Carr A, Gross A S, Hoskins J M, Penny R, Cooper D A

Abstract excerpt

OBJECTIVE: Hypersensitivity to trimethoprim-sulphamethoxazole (TMP-SMX) is more common in patients with HIV infection. In non-infected patients, TMP-SMX hypersensitivity is more common in those with a slow acetylator phenotype. This study was conducted to determine whether the slow acetylation ph...

Topics

Acetylation
Adult
Arylamine N-Acetyltransferase
Caffeine
Drug Eruptions
Female
HIV Infections
Humans
Male
Middle Aged
Phenotype
Risk Factors
Trimethoprim, Sulfamethoxazole Drug Combination

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