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Article

Slow acetylator phenotype and genotype in HIV-positive patients with sulphamethoxazole hypersensitivity.

British journal of clinical pharmacology - 1 Feb 2003

Alfirevic Ana, Stalford Anne C, Vilar F Javier, Wilkins Ed G L, Park B Kevin, Pirmohamed Munir

Abstract excerpt

AIMS: To test the role of acetylator status, and to investigate the reported discrepancy between acetylator phenotype and genotype in HIV-positive patients with sulphamethoxazole (SMX) hypersensitivity. METHODS: Forty HIV-positive patients (32 of whom were SMX-hypersensitive), and 26 healthy volunteers, were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12580987
DOI: 10.1046/j.1365-2125.2003.01754.x
PMCID: PMC1894729

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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