Article
N-acetyltransferase 2 polymorphism in patients infected with human immunodeficiency virus.
Clinical pharmacology and therapeutics - 1 Jul 1996
Kaufmann G R, Wenk M, Taeschner W, Peterli B, Gyr K, Meyer U A, Haefeli W E
Abstract excerpt
OBJECTIVES: To evaluate the prevalence of slow acetylation of hepatic N-acetyltransferase 2 (NAT2) in patients with different stages of human immunodeficiency virus (HIV) infection, to assess the relationship between acetylation capacity and the degree of immunosuppression, and to study the concordance between NAT2 phenotype and genotype. METHODS: This prospective study in a consecutive sample of HIV-infected...
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