Article
Verified predominance of slow acetylator phenotype N-acetyltransferase 2 (NAT2) in a Hmong population residing in Minnesota.
Biopharmaceutics & drug disposition - 1 Sept 2006
Straka Robert J, Burkhardt R Todd, Lang Nicholas P, Vang Ter, Hadsall Kelly Z, Tsai Michael Y
Abstract excerpt
Southeast Asians known as the Hmong have a high prevalence of tuberculosis and select cancers. The slow acetylation (SA) phenotype for N-acetyltransferase 2 (NAT2) has been associated with toxicity from the anti-tuberculosis drug, isoniazid and in increased risk of select cancers. Previous research indicates a 74.5% prevalence of SA in Hmong which differs from other Asian populations including the Japanese and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
