Article
N-acetylation among HIV-positive patients and patients with AIDS: when is fast, fast and slow, slow?
Clinical pharmacology and therapeutics - 1 Sept 1997
O'Neil W M, Gilfix B M, DiGirolamo A, Tsoukas C M, Wainer I W
Abstract excerpt
BACKGROUND: The discrepancy between genotype and expressed phenotype of the polymorphic N-acetyltransferase (NAT2) has been suggested by separate genotypic and phenotypic studies in populations with human immunodeficiency virus (HIV). Only one study has examined both genotype and phenotype in the same population, and no discrepancies were observed. METHODS: In a cross-sectional study, 105 HIV-positive patients...
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