Analysis of allele-specific contact sites of natural HLA-DR17 ligands.

Article

Analysis of allele-specific contact sites of natural HLA-DR17 ligands.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 1994

Malcherek G, Gnau V, Stevanovic S, Rammensee H G, Jung G, Melms A

Abstract excerpt

The sequence motif of peptide ligands naturally associated with DR17 has indicated conserved residues at the relative positions P1-P4-P6-P 8.9 or 10. Eight naturally processed DR17 ligands were synthesized to study the role of conserved residues in DR17 binding. In their majority, they showed an...

Topics

Alleles
Amino Acid Sequence
Antigens
Apolipoproteins B
Binding Sites
HLA-DR Antigens
Humans
In Vitro Techniques
Ligands
Molecular Sequence Data
Structure-Activity Relationship
alpha 1-Antitrypsin

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