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Article

Analysis of allele-specific contact sites of natural HLA-DR17 ligands.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 1994

Malcherek G, Gnau V, Stevanovic S, Rammensee H G, Jung G, Melms A

Abstract excerpt

The sequence motif of peptide ligands naturally associated with DR17 has indicated conserved residues at the relative positions P1-P4-P6-P 8.9 or 10. Eight naturally processed DR17 ligands were synthesized to study the role of conserved residues in DR17 binding. In their majority, they showed an excellent ability to bind to purified DR17 molecules. Binding experiments with variant peptides confirmed aspartate as...

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PMID: 8027545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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