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Article

Expression and function of Pax 1 during development of the pectoral girdle.

Development (Cambridge, England) - 1 Oct 1994

Timmons P M, Wallin J, Rigby P W, Balling R

Abstract excerpt

Pax 1 is a member of the paired-box containing gene family. Expression has previously been observed in the developing sclerotomes and later in the anlagen of the intervertebral discs. Analysis of Pax 1-deficient undulated mice revealed an important role for this gene in the development of the axial skeleton, in which Pax 1 apparently functions as a mediator of notochordal signals during sclerotome...

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Identifiers

PMID: 7607069
DOI: 10.1242/dev.120.10.2773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression and function of Pax 1 during development of the pectoral girdle.PMID 7607069Read ↗

The role of Pax-1 in axial skeleton development.Semantic proximity Read ↗

Development of the skeletal system.Semantic proximity Read ↗

Cooperation of Hoxa5 and Pax1 genes during formation of the pectoral girdle.Semantic proximity Read ↗

A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae.Semantic proximity Read ↗

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.Semantic proximity Read ↗

Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development.Semantic proximity Read ↗

The role of the notochord for epaxial myotome formation in the mouse.Semantic proximity Read ↗

undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures.Semantic proximity Read ↗

Pax1 and Pax9 synergistically regulate vertebral column development.Semantic proximity Read ↗

Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency.Semantic proximity Read ↗

Hox genes maintain critical roles in the adult skeletonSemantic proximity Read ↗

Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis.Semantic proximity Read ↗

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