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Article

Profilin1 regulates sternum development and endochondral bone formation.

The Journal of biological chemistry - 28 Sept 2012

Miyajima Daisuke, Hayata Tadayoshi, Suzuki Takafumi, Hemmi Hiroaki, Nakamoto Tetsuya, Notomi Takuya, Amagasa Teruo, Böttcher Ralph T, Costell Mercedes, Fässler Reinhard, Ezura Yoichi, Noda Masaki

Abstract excerpt

Bone development is a dynamic process that requires cell motility and morphological adaptation under the control of actin cytoskeleton. This actin cytoskeleton system is regulated by critical modulators including actin-binding proteins. Among them, profilin1 (Pfn1) is a key player to control actin fiber structure, and it is involved in a number of cellular activities such as migration. During the early phase of...

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Identifiers

PMID: 22773831
DOI: 10.1074/jbc.M111.329938
PMCID: PMC3460455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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