Article
undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures.
Developmental biology - 1 Feb 1995
Dietrich S, Gruss P
Abstract excerpt
undulated extensive mice carry a deletion of at least 28.2 kb, removing the terminal Pax-1 exon including the poly(A) signal. This mutation leads to a drastically reduced amount of Pax-1 transcript. The similarity in phenotype between unex and the point mutation un suggests both to be functionall...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- DNA
- DNA Mutational Analysis
- DNA-Binding Proteins
- Drosophila
- Exons
- Female
- Gene Expression Regulation, Developmental
- Introns
- Male
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Paired Box Transcription Factors
- Phenotype