Article
Chronic hypoxia impairs the differentiation of 3T3-L1 fibroblast in culture: role of sustained protein kinase C activation.
Journal of cellular physiology - 1 Jul 1994
Sahai A, Patel M S, Zavosh A S, Tannen R L
Abstract excerpt
The effect of hypoxia on 3T3-L1 cell differentiation was examined in confluent cultures incubated with differentiation medium (DM) followed by incubation in growth medium (GM). Control cultures remained in GM throughout the incubation period. Eight days after the incubation, cells were assessed e...
Topics
- 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
- Alkaloids
- Animals
- Cell Differentiation
- Cell Division
- Cell Line
- Enzyme Activation
- Fibroblasts
- Hypoxia
- Isoquinolines
- Mice
- Phenotype
- Piperazines
- Protein Kinase C
- Staurosporine