Article
Novel roles for protein kinase Cdelta-dependent signaling pathways in acute hypoxic stress-induced autophagy.
The Journal of biological chemistry - 5 Dec 2008
Chen Jo-Lin, Lin Her H, Kim Kwang-Jin, Lin Anning, Forman Henry J, Ann David K
Abstract excerpt
Macroautophagy, a tightly orchestrated intracellular process for bulk degradation of cytoplasmic proteins or organelles, is believed to be essential for cell survival or death in response to stress conditions. Recent observations indicate that autophagy is an adaptive response in cells subjected to prolonged hypoxia. However, the signaling mechanisms that activate autophagy under acute hypoxic stress are not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.