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Article

Loss of heterozygosity is related to p53 mutations and smoking in lung cancer.

British journal of cancer - 1 Jan 2001

Zienolddiny S, Ryberg D, Arab M O, Skaug V, Haugen A

Abstract excerpt

Carcinogenesis results from an accumulation of several genetic alterations. Mutations in the p53 gene are frequent and occur at an early stage of lung carcinogenesis. Loss of multiple chromosomal regions is another genetic alteration frequently found in lung tumours. We have examined the association between p53 mutations, loss of heterozygosity (LOH) at frequently deleted loci in lung cancer, and tobacco exposure...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11161381
DOI: 10.1054/bjoc.2000.1528
PMCID: PMC2363705

Genes

FHIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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