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Article

Alteration of the substrate specificity of human lysozyme by site-specific intermolecular cross-linking.

FEBS letters - 5 Dec 1994

Muraki M, Jigami Y, Harata K

Abstract excerpt

Human lysozyme dimers were prepared by the intermolecular cross-linking of the monomer that contained the mutation of either Arg41 to Cys or Ala73 to Cys with a divalent maleimide compound. Among the three kinds of possible dimers only R41C-R41C dimer, in which the two catalytic clefts can come close to each other due to the proximity of the conjugation site to the active sites, turned out to be 2.3 times more...

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Identifiers

PMID: 7988687
DOI: 10.1016/0014-5793(94)01168-0

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PNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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