Article
Heritable trinucleotide repeats and neurological disorders.
Experientia - 30 Nov 1994
Shastry B S
Abstract excerpt
In the past 3 years, seven human neurological disorders have been found to be associated with an abnormal number of unstable trinucleotide repeats within exons or non-expressed regions of a gene. These forms of mutations are called dynamic mutations. The expansion in copy number of trinucleotide...
Topics
- Animals
- Cerebellar Ataxia
- Fragile X Syndrome
- Humans
- Huntington Disease
- Muscular Atrophy, Spinal
- Mutation
- Myotonic Dystrophy
- Nervous System Diseases
- Repetitive Sequences, Nucleic Acid