Article
[Genetic diseases and unstable expansions of trinucleotide repeats].
La Revue du praticien - 15 Jan 1997
Mandel J L
Abstract excerpt
More than 10 genetic diseases, including 3 frequent ones (the fragile X mental retardation syndrome, myotonic dystrophy and Huntington's disease) are caused by unstable expansions of trinucleotide repeats. The instability of these mutations and their strong tendency to further expansion, account...
Topics
- DNA
- Fragile X Syndrome
- Friedreich Ataxia
- Humans
- Huntington Disease
- Mutation
- Myotonic Dystrophy
- Trinucleotide Repeats