Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trinucleotide repeat disorders.

Annual review of neuroscience - 1 Jan 2007

Orr Harry T, Zoghbi Huda Y

Abstract excerpt

The discovery that expansion of unstable repeats can cause a variety of neurological disorders has changed the landscape of disease-oriented research for several forms of mental retardation, Huntington disease, inherited ataxias, and muscular dystrophy. The dynamic nature of these mutations provided an explanation for the variable phenotype expressivity within a family. Beyond diagnosis and genetic counseling,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Cerebellar Ataxia
Share to Fragile X Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Heredodegenerative Disorders, Nervous System

Share to Huntington Disease

Share to Peptides

Share to Trinucleotide Repeat Expansion

Source

Identifiers

PMID: 17417937
DOI: 10.1146/annurev.neuro.29.051605.113042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trinucleotide repeat disorders.PMID 17417937Read ↗

Trinucleotide repeats: mechanisms and pathophysiology.Semantic proximity Read ↗

Fourteen and counting: unraveling trinucleotide repeat diseasesSemantic proximity Read ↗

Trinucleotide repeat expansion and neuropsychiatric disease.Semantic proximity Read ↗

The complex pathology of trinucleotide repeats.Semantic proximity Read ↗

Trinucleotide repeat disorders in humans: discussions of mechanisms and medical issues.Semantic proximity Read ↗

Fragile X and other trinucleotide repeat diseases.Semantic proximity Read ↗

Molecular mechanisms underlying nucleotide repeat expansion disorders.Semantic proximity Read ↗

DNA trinucleotide repeat expansion in neuropsychiatric patients.Semantic proximity Read ↗

Trinucleotide repeats and neurodegenerative disease.Semantic proximity Read ↗

Repeat expansion diseases: when a good RNA turns bad.Semantic proximity Read ↗

Genes with triplet repeats: a new class of mutations causing neurological diseases.Semantic proximity Read ↗

RNA-mediated neurodegeneration in repeat expansion disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.