Article
The complex pathology of trinucleotide repeats.
Current opinion in cell biology - 1 Jun 1997
Reddy P S, Housman D E
Abstract excerpt
The expansion of trinucleotide repeat sequences has now been shown to be the underlying cause of at least ten human disorders. Unifying features among these diseases include the unstable behavior of the triplet repeat during germline transmission when the length of the repeat exceeds a critical v...
Topics
- Animals
- Disease Models, Animal
- Fragile X Syndrome
- Friedreich Ataxia
- Genetic Diseases, Inborn
- Humans
- Introns
- Mice
- Mutation
- Myotonic Dystrophy
- Peptides
- RNA-Binding Proteins
- Trinucleotide Repeats