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Article

Trinucleotide repeats and genome variation.

Current opinion in genetics & development - 1 Jun 1993

Kuhl D P, Caskey C T

Abstract excerpt

The recent cloning of several disease genes has identified the instability of trinucleotide repeats as a fundamental mechanism for variation within the human genome. This mutation mechanism explains the unique inheritance characteristics of the diseases it causes, and there is a significant potential that this mechanism is involved in the pathogenesis of other, as yet uncharacterized, genetic diseases.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Repetitive Sequences, Nucleic Acid

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Identifiers

PMID: 8353413
DOI: 10.1016/0959-437x(93)90112-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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