Article
Fragile X and other trinucleotide repeat diseases.
Obstetrics and gynecology clinics of North America - 1 Jun 2002
Wenstrom Katharine D
Abstract excerpt
Hereditary unstable DNA is composed of strings of trinucleotide repeats, in which three nucleotides are repeated over and over (ie CAGCAGCAGCAG). These repeats are found in several sites within genes; depending on their location, the number of triplet repeats in a string can change as it is passed on to offspring. When the number of repeats increases to a critical size, it can have a variety of affects on gene...
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