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Article

Genetic analysis of liver tumorigenesis in SV40 T antigen transgenic mice implies a role for imprinted genes.

Cancer research - 15 Dec 1994

Held W A, Pazik J, O'Brien J G, Kerns K, Gobey M, Meis R, Kenny L, Rustum Y

Abstract excerpt

Liver tumors from interspecific hybrid, transgenic mice containing the SV40 early region linked to a mouse major urinary protein enhancer/promoter were analyzed for loss of heterozygosity to identify chromosomal regions which potentially contain genetic loci involved in multistep tumorigenesis. A broad pattern of complete and partial loss of heterozygosity or allelic imbalance was observed with frequent loss of...

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PMID: 7987847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Genetic analysis of liver tumorigenesis in SV40 T antigen transgenic mice implies a role for imprinted genes.PMID 7987847Read ↗

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