Frequency of IFN beta 1 gene loss in 47 primary human gliomas.

Article

Frequency of IFN beta 1 gene loss in 47 primary human gliomas.

Noshuyo byori = Brain tumor pathology - 1 Jan 1993

Sugawa N, Ekstrand A J, Ueda S, Collins V P

Abstract excerpt

Loss of genetic information from a number of specific regions of the genome has been documented in primary human gliomas. Recently loss of heterozygosity or nullizygosity of the IFN beta 1 gene has been found in glioblastomas. We used Restriction Fragment Length Polymorphism (RFLP) analysis in or...

Topics

Adolescent
Adult
Aged
Alleles
Autoradiography
Child
Child, Preschool
Chromosome Mapping
DNA, Neoplasm
Densitometry
Gene Deletion
Glioma
Humans
Interferon-beta
Middle Aged
Nucleic Acid Hybridization
Polymorphism, Restriction Fragment Length

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