Article
Avian myeloblastic cell lines transformed by two nuclear oncoproteins, P135gag-myb-ets and p61/63myc: a model of retinoic acid-induced differentiation not abrogated by v-erbA.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Aug 1994
al Moustafa A E, Gautier R, Saule S, Dieterlen-Lièvre F, Cormier F
Abstract excerpt
We previously demonstrated that the retroviral construct MHE226 transducing both the P135gag-myb-ets and p61/63myc nuclear proteins induces solid hemopoietic tumors in early chicken embryos. In the present paper, we report the characterization of two MHE226-transformed cell lines established from...
Topics
- Animals
- Avian Myeloblastosis Virus
- Cell Differentiation
- Cell Line, Transformed
- Chick Embryo
- Models, Biological
- Nuclear Proteins
- Oncogene Proteins v-myb
- Phenotype
- Proto-Oncogene Proteins c-myc
- Retroviridae Proteins, Oncogenic
- Tretinoin