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Article

v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent haematopoietic progenitors.

The EMBO journal - 15 Jun 1995

Frampton J, McNagny K, Sieweke M, Philip A, Smith G, Graf T

Abstract excerpt

The E26 avian leukaemia virus encodes a fusion oncoprotein consisting of truncated versions of the c-Myb and c-Ets-1 transcription factors. When used to infect embryonic chicken haematopoietic cells two types of self-renewing progenitors are obtained, namely myeloblasts and 'MEPs' (Myb-Ets progenitors). In earlier work we have shown that myeloblasts transformed by the ts21 mutant of E26, which has a lesion in...

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Identifiers

PMID: 7540977
DOI: 10.1002/j.1460-2075.1995.tb07286.x
PMCID: PMC398405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent haematopoietic progenitors.PMID 7540977Read ↗

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Transformation by v-myb correlates with trans-activation of gene expression.Semantic proximity Read ↗

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